Indian Journal of Paediatric Dermatology

REVIEW ARTICLE
Year
: 2022  |  Volume : 23  |  Issue : 1  |  Page : 8--23

Antihistamines in children: A dermatological perspective


Sakshi Kohli, Richa Tayal, Tarang Goyal 
 Department of Dermatology, Venereology and Leprosy, Muzaffarnagar Medical College and Hospital, Muzaffarnagar, Uttar Pradesh, India

Correspondence Address:
Tarang Goyal
Department of Dermatology, Venereology and Leprosy, Muzaffarnagar Medical College and Hospital, Muzaffarnagar, Uttar Pradesh
India

Antihistamines are widely used drugs in pediatric population. First-generation antihistamines have been in use since last many years, though adequate data on their efficacy and safety in pediatric population is scarce. In contrast, second-generation antihistamines have been studied extensively in children and have a better safety profile with more receptor selectivity and less adverse effects. Pruritus has a significant impact on the quality of life in children and its management is of paramount importance. This article reviews the first and second-generation antihistamines in the light of recent advances in the understanding of their pharmacological properties and safety profile in children. An extensive literature search was done; all clinical trials, randomized double-blinded or single-blinded controlled trials, open-label studies, retrospective studies, reviews, case series, and case reports focusing on the use of antihistamines in pediatric age groups were screened. The selected articles were retrieved; the final manuscript was prepared, analyzed, and presented in a narrative fashion.


How to cite this article:
Kohli S, Tayal R, Goyal T. Antihistamines in children: A dermatological perspective.Indian J Paediatr Dermatol 2022;23:8-23


How to cite this URL:
Kohli S, Tayal R, Goyal T. Antihistamines in children: A dermatological perspective. Indian J Paediatr Dermatol [serial online] 2022 [cited 2022 Jan 28 ];23:8-23
Available from: https://www.ijpd.in/article.asp?issn=2319-7250;year=2022;volume=23;issue=1;spage=8;epage=23;aulast=Kohli;type=0